Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls

BACKGROUND: Recent genome-wide association studies (GWAS) of myocardial infarction (MI) and other forms of coronary artery disease (CAD) have led to the discovery of at least 13 genetic loci. In addition to the effect size, power to detect associations is largely driven by sample size. Therefore, to...

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Auteurs principaux: Preuss, Michael, König, Inke R., Thompson, John R., Erdmann, Jeanette, Absher, Devin, Assimes, Themistocles L., Blankenberg, Stefan, Boerwinkle, Eric, Chen, Li, Cupples, L. Adrienne, Hall, Alistair S., Halperin, Eran, Hengstenberg, Christian, Holm, Hilma, Laaksonen, Reijo, Li, Mingyao, März, Winfried, McPherson, Ruth, Musunuru, Kiran, Nelson, Christopher P., Burnett, Mary Susan, Epstein, Stephen E., O’Donnell, Christopher J., Quertermous, Thomas, Rader, Daniel J., Roberts, Robert, Schillert, Arne, Stefansson, Kari, Stewart, Alexandre F.R., Thorleifsson, Gudmar, Voight, Benjamin F., Wells, George A., Ziegler, Andreas, Kathiresan, Sekar, Reilly, Muredach P., Samani, Nilesh J., Schunkert, Heribert
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070269/
https://ncbi.nlm.nih.gov/pubmed/20923989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.109.899443
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