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1,25-Dihydroxyvitamin D(3) Reduces TGF-β3-Induced Fibrosis-Related Gene Expression in Human Uterine Leiomyoma Cells

BACKGROUND: Uterine leiomyomas (fibroids) are the most common benign estrogen-dependent tumors of premenopausal women. TGF-β3 up-regulates the synthesis of many of extracellular matrix proteins that are associated with tissue fibrosis. OBJECTIVE: To examine the effect of 1,25-dihydroxyvitamin D(3) (...

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Detalhes bibliográficos
Main Authors: Halder, Sunil K., Goodwin, J. Shawn, Al-Hendy, Ayman
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070259/
https://ncbi.nlm.nih.gov/pubmed/21289245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2131
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