Distinct HDL subclasses present similar intrinsic susceptibility to oxidation by HOCl

The heme protein myeloperoxidase (MPO) functions as a catalyst for lipoprotein oxidation. Hypochlorous acid (HOCl), a potent two-electron oxidant formed by the MPO–H(2)O(2)–chloride system of activated phagocytes, modifies antiatherogenic high-density lipoprotein (HDL). The structural heterogeneity...

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Bibliografiske detaljer
Main Authors: Chantepie, Sandrine, Malle, Ernst, Sattler, Wolfgang, Chapman, M. John, Kontush, Anatol
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070237/
https://ncbi.nlm.nih.gov/pubmed/19464255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.05.005
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