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Normal Modes of Prion Proteins: From Native to Infectious particle
Prion proteins (PrP) are the infectious agent in transmissible spongiform encephalopathies (i.e. mad cow disease). To be infectious, prion proteins must undergo a conformational change involving a decrease of α-helical content along with an increase of β-strand structure. This conformational change...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070235/ https://ncbi.nlm.nih.gov/pubmed/21338080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1010514 |
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