Alcohol Facilitates CD1d Loading, Subsequent Activation of NKT Cells, and Reduces the Incidence of Diabetes in NOD Mice

BACKGROUND: Ethanol (‘alcohol’) is a partly hydrophobic detergent that may affect the accessibility of glycolipids thereby influencing immunological effects of these molecules. METHODS: The study included cellular in vitro tests using α-galactosylceramide (αGalCer), and in vivo NOD mice experiments...

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Autori principali: Buschard, Karsten, Hansen, Axel Kornerup, Jensen, Karen, Lindenbergh-Kortleve, Dicky J., de Ruiter, Lilian F., Krohn, Thomas C., Hufeldt, Majbritt R., Vogensen, Finn K., Aasted, Bent, Osterbye, Thomas, Roep, Bart O., de Haar, Colin, Nieuwenhuis, Edward E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069977/
https://ncbi.nlm.nih.gov/pubmed/21483778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017931
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