Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules

For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (Fusion protein), Rabies virus (Glycoprotein)...

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Detalhes bibliográficos
Main Authors: Hultberg, Anna, Temperton, Nigel J., Rosseels, Valérie, Koenders, Mireille, Gonzalez-Pajuelo, Maria, Schepens, Bert, Ibañez, Lorena Itatí, Vanlandschoot, Peter, Schillemans, Joris, Saunders, Michael, Weiss, Robin A., Saelens, Xavier, Melero, José A., Verrips, C. Theo, Van Gucht, Steven, de Haard, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069976/
https://ncbi.nlm.nih.gov/pubmed/21483777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017665
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