UV-B Radiation Induces Macrophage Migration Inhibitory Factor–Mediated Melanogenesis through Activation of Protease-Activated Receptor-2 and Stem Cell Factor in Keratinocytes

UV radiation indirectly regulates melanogenesis in melanocytes through a paracrine regulatory mechanism involving keratinocytes. Protease-activated receptor (PAR)-2 activation induces melanosome transfer by increasing phagocytosis of melanosomes by keratinocytes. This study demonstrated that macroph...

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Detalhes bibliográficos
Main Authors: Enomoto, Akiko, Yoshihisa, Yoko, Yamakoshi, Takako, Ur Rehman, Mati, Norisugi, Osamu, Hara, Hiroshi, Matsunaga, Kenji, Makino, Teruhiko, Nishihira, Jun, Shimizu, Tadamichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069914/
https://ncbi.nlm.nih.gov/pubmed/21281800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.021
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