Bone Marrow–Derived Progenitor Cells Do Not Contribute to Podocyte Turnover in the Puromycin Aminoglycoside and Renal Ablation Models in Rats

A key event in the progression of glomerular disease is podocyte loss that leads to focal and segmental glomerulosclerosis (FSGS). Because adult podocytes are postmitotic cells, podocyte replacement by bone marrow–derived progenitors could prevent podocytopenia and FSGS. This study uses double immun...

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Bibliographische Detailangaben
Hauptverfasser: Meyer-Schwesinger, Catherine, Lange, Claudia, Bröcker, Verena, Agustian, Putri Andina, Lehmann, Ulrich, Raabe, Annette, Brinkmeyer, Martina, Kobayashi, Eiji, Schiffer, Mario, Büsche, Guntram, Kreipe, Hans H., Thaiss, Friedrich, Becker, Jan U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069901/
https://ncbi.nlm.nih.gov/pubmed/21281782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.024
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