Δ-PCR, A Simple Method to Detect Translocations and Insertion/Deletion Mutations

PCR detection of chromosomal translocations and small insertion/deletion mutations is challenging when potential amplicon size varies greatly. Molecular diagnostic laboratories face such difficulties with the BCL2-IGH translocation in follicular lymphoma and with internal tandem duplication mutation...

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Main Authors: Lin, Ming-Tseh, Tseng, Li-Hui, Rich, Roy G., Hafez, Michael J., Harada, Shuko, Murphy, Kathleen M., Eshleman, James R., Gocke, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069866/
https://ncbi.nlm.nih.gov/pubmed/21227398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.11.004
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