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Finding a needle in a haystack: whole genome sequencing and mutation discovery in murine models
Acute promyelocytic leukemia (APL) is a malignancy of the bone marrow, in which there is a deficiency of myeloid cells and an excess of immature cells called promyelocytes. APL is most commonly caused by a translocation (15:17) and expression of the promyelocytic leukemia and the retinoic receptor α...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069796/ https://ncbi.nlm.nih.gov/pubmed/21436577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57200 |
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