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CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions

Hemolytic transfusion reactions (HTRs) can produce serious and potentially life-threatening complications in sickle cell disease (SCD) patients; however, the mechanisms underlying these complications remain undetermined. We established a model of alloimmune, IgG-mediated HTRs in a well-characterized...

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Detalhes bibliográficos
Main Authors: Jang, Jung-Eun, Hod, Eldad A., Spitalnik, Steven L., Frenette, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069787/
https://ncbi.nlm.nih.gov/pubmed/21383500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45336
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