FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer

The limited success of cancer immunotherapy is often attributed to the loss of antigen-specific T cell function in situ. However, the mechanism for this loss of function is unknown. In this study, we describe a population of tumor-associated DCs (TADCs) in both human and mouse prostate cancer that t...

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Detalhes bibliográficos
Main Authors: Watkins, Stephanie K., Zhu, Ziqiang, Riboldi, Elena, Shafer-Weaver, Kim A., Stagliano, Katherine E.R., Sklavos, Martha M., Ambs, Stefan, Yagita, Hideo, Hurwitz, Arthur A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069771/
https://ncbi.nlm.nih.gov/pubmed/21436588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44325
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