The level of the pUB110 replication initiator protein is autoregulated, which provides an additional control for plasmid copy number.
Plasmids control their copy number by limiting the amount of the initiator for DNA replication. The plasmid pUB110 initiator protein is termed RepU. Expression of the pUB110 repU gene is controlled by two antisense RNAs that interfere with repU mRNA translation. Genetic evidence suggests that Rep pr...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1995
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7596815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.11.1894 |
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