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Involvement of DNA-dependent Protein Kinase in Normal Cell Cycle Progression through Mitosis
The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) plays an important role in DNA double-strand break (DSB) repair as the underlying mechanism of the non-homologous end joining pathway. When DSBs occur, DNA-PKcs is rapidly phosphorylated at both the Thr-2609 and Ser-2056 residues, and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069479/ https://ncbi.nlm.nih.gov/pubmed/21330363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212969 |
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