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Involvement of DNA-dependent Protein Kinase in Normal Cell Cycle Progression through Mitosis

The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) plays an important role in DNA double-strand break (DSB) repair as the underlying mechanism of the non-homologous end joining pathway. When DSBs occur, DNA-PKcs is rapidly phosphorylated at both the Thr-2609 and Ser-2056 residues, and...

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Bibliografski detalji
Glavni autori: Lee, Kyung-Jong, Lin, Yu-Fen, Chou, Han-Yi, Yajima, Hirohiko, Fattah, Kazi R., Lee, Sheng-Chung, Chen, Benjamin P. C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069479/
https://ncbi.nlm.nih.gov/pubmed/21330363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.212969
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