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Structure of a Ca(2+)-Myristoyl Switch Protein That Controls Activation of a Phosphatidylinositol 4-Kinase in Fission Yeast

Neuronal calcium sensor (NCS) proteins transduce Ca(2+) signals and are highly conserved from yeast to humans. We determined NMR structures of the NCS-1 homolog from fission yeast (Ncs1), which activates a phosphatidylinositol 4-kinase. Ncs1 contains an α-NH(2)-linked myristoyl group on a long N-ter...

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Detalhes bibliográficos
Main Authors: Lim, Sunghyuk, Strahl, Thomas, Thorner, Jeremy, Ames, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069458/
https://ncbi.nlm.nih.gov/pubmed/21288895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208868
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