Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretion in Vitro

Cellular oxygen consumption is a determinant of intracellular oxygen levels. Because of the high demand of mitochondrial respiration during insulin secretion, pancreatic β-cells consume large amounts of oxygen in a short time period. We examined the effect of insulin secretion on cellular oxygen ten...

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Détails bibliographiques
Auteurs principaux: Sato, Yoshifumi, Endo, Hiroko, Okuyama, Hiroaki, Takeda, Takaaki, Iwahashi, Hiromi, Imagawa, Akihisa, Yamagata, Kazuya, Shimomura, Iichiro, Inoue, Masahiro
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Metabolism
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069454/
https://ncbi.nlm.nih.gov/pubmed/21296882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.194738
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