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Contractility Dominates Adhesive Ligand Density in Regulating Cellular De-adhesion and Retraction Kinetics

Cells that are enzymatically detached from a solid substrate rapidly round up as the tensile prestress in the cytoskeleton is suddenly unopposed by cell–ECM adhesions. We recently showed that this retraction follows sigmoidal kinetics with time constants that correlate closely with cortical stiffnes...

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Bibliografische gegevens
Hoofdauteurs: Sen, Shamik, Ng, Win Pin, Kumar, Sanjay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069333/
https://ncbi.nlm.nih.gov/pubmed/21046466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-010-0195-z
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