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Cleavage of the HIV replication primer tRNALys,3 in human cells expressing bacterial anticodon nuclease.

Anticodon nuclease is a bacterial restriction enzyme directed against tRNA(Lys). We report that anticodon nuclease also cleaves mammalian tRNA(Lys) molecules, with preference and site specificity shown towards the natural substrate. Expression of the anticodon nuclease core polypeptide PrrC in HeLa...

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Autori principali: Shterman, N, Elroy-Stein, O, Morad, I, Amitsur, M, Kaufmann, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC306931/
https://ncbi.nlm.nih.gov/pubmed/7784179
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