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Genetic visualization with an improved GCaMP calcium indicator reveals spatiotemporal activation of the spinal motor neurons in zebrafish

Animal behaviors are generated by well-coordinated activation of neural circuits. In zebrafish, embryos start to show spontaneous muscle contractions at 17 to 19 h postfertilization. To visualize how motor circuits in the spinal cord are activated during this behavior, we developed GCaMP-HS (GCaMP-h...

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Bibliografiske detaljer
Main Authors: Muto, Akira, Ohkura, Masamichi, Kotani, Tomoya, Higashijima, Shin-ichi, Nakai, Junichi, Kawakami, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069178/
https://ncbi.nlm.nih.gov/pubmed/21383146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000887108
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