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Altered Dopamine and Serotonin Metabolism in Motorically Asymptomatic R6/2 Mice

The pattern of cerebral dopamine (DA) abnormalities in Huntington disease (HD) is complex, as reflected by the variable clinical benefit of both DA antagonists and agonists in treating HD symptoms. In addition, little is known about serotonin metabolism despite the early occurrence of anxiety and de...

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Autors principals: Mochel, Fanny, Durant, Brandon, Durr, Alexandra, Schiffmann, Raphael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069081/
https://ncbi.nlm.nih.gov/pubmed/21483838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018336
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