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Mycobacterium tuberculosis Induces an Atypical Cell Death Mode to Escape from Infected Macrophages

BACKGROUND: Macrophage cell death following infection with Mycobacterium tuberculosis plays a central role in tuberculosis disease pathogenesis. Certain attenuated strains induce extrinsic apoptosis of infected macrophages but virulent strains of M. tuberculosis suppress this host response. We previ...

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Autori principali: Lee, Jinhee, Repasy, Teresa, Papavinasasundaram, Kadamba, Sassetti, Christopher, Kornfeld, Hardy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069075/
https://ncbi.nlm.nih.gov/pubmed/21483832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018367
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