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Identification of a Cryptic Prokaryotic Promoter within the cDNA Encoding the 5′ End of Dengue Virus RNA Genome

Infectious cDNA clones of RNA viruses are important research tools, but flavivirus cDNA clones have proven difficult to assemble and propagate in bacteria. This has been attributed to genetic instability and/or host cell toxicity, however the mechanism leading to these difficulties has not been full...

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Detalhes bibliográficos
Main Authors: Li, Dongsheng, Aaskov, John, Lott, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069047/
https://ncbi.nlm.nih.gov/pubmed/21483867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018197
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