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The posttranslational modification of tubulin undergoes a switch from detyrosination to acetylation as epithelial cells become polarized

Tubulin posttranslational modifications (PTMs) have been suggested to provide navigational cues for molecular motors to deliver cargo to spatially segregated subcellular domains, but the molecular details of this process remain unclear. Here we show that in Madin-Darby Canine Kidney (MDCK) epithelia...

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Hlavní autoři: Quinones, Geraldine B., Danowski, Barbara A., Devaraj, Anjan, Singh, Vimla, Ligon, Lee A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069008/
https://ncbi.nlm.nih.gov/pubmed/21307336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-06-0519
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