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Tandem repeats of the 5' non-transcribed spacer of Tetrahymena rDNA function as high copy number autonomous replicons in the macronucleus but do not prevent rRNA gene dosage regulation.

The rRNA genes in the somatic macronucleus of Tetrahymena thermophila are normally on 21 kb linear palindromic molecules (rDNA). We examined the effect on rRNA gene dosage of transforming T.thermophila macronuclei with plasmid constructs containing a pair of tandemly repeated rDNA replication origin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pan, W J, Blackburn, E H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC306898/
https://ncbi.nlm.nih.gov/pubmed/7784211
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