Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells

BACKGROUND: Autotaxin (ATX) possesses lysophospholipase D (lyso PLD) activity, which converts lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA). The ATX-LPA signaling axis has been implicated in angiogenesis, chronic inflammation and tumor progression. Osteopontin (OPN) is an important...

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Detalhes bibliográficos
Main Authors: Zhang, Rihua, Wang, Jing, Ma, Shijie, Huang, Zuhu, Zhang, Guoxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068946/
https://ncbi.nlm.nih.gov/pubmed/21406114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-11
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