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Double suicide genes driven by kinase domain insert containing receptor promoter selectively kill human lung cancer cells

BACKGROUND: To investigate the selective killing efficacy of the double suicide genes driven by KDR promoter. MATERIALS AND METHODS: A double suicide gene system with the KDR promoter, pcDNA3-KDRp-CDglyTK, was constructed and transfected into lung cancer cell lines L9981 and NL9980, and human hepato...

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Detalhes bibliográficos
Main Authors: Ma, Junrong, Li, Mi, Mei, Longyong, Zhou, Qinghua, Liu, Lunxu, Yu, Xijie, Che, Guowei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068930/
https://ncbi.nlm.nih.gov/pubmed/21418659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-9-6
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