Combined Impact of Polymorphism of Folate Metabolism Genes; Glutamate Carboxypeptidase, Methylene Tetrahydrofolate Reductase and Methionine Synthase Reductase on Breast Cancer Susceptibility in Kashmiri Women

BACKGROUND: Folate and methionine play a crucial role in DNA synthesis, repair and the epigenetic profile of cell. Hence, the alterations in the folate metabolism can lead to aberrant proliferation leading to neoplasia. Most of the studies have associated polymorphisms in methylene tetrahydrofolate...

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Main Authors: Mir, M. Muzaffar, Dar, Javid A., Dar, Nazir A., Dar, M. Shafi, Salam, Irfana, Lone, M. Maqbool, Chowdary, Nissar A.
格式: Artigo
語言:Inglês
出版: Qassim University, Kingdom of Saudi Arabia 2008
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068715/
https://ncbi.nlm.nih.gov/pubmed/21475466
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