Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulation

Mycobacterium tuberculosis serine/threonine protein kinases (STPKs) are key regulators of growth and metabolism; however, evidence for their roles in virulence is limited. In a preliminary screen based on comparative expression between strains H37Rv and H37Ra, six STPK genes, pknD, pknG, pknH, pknJ,...

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Autors principals: Malhotra, Vandana, Arteaga-Cortés, Lourdes T., Clay, Gwendolyn, Clark-Curtiss, Josephine E.
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2010
Matèries:
Microbial Pathogenicity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068690/
https://ncbi.nlm.nih.gov/pubmed/20522497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.040675-0
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