Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis

Synthesis of the siderophore yersiniabactin (Ybt) proceeds by a mixed nonribosomal peptide synthetase/polyketide synthase mechanism. Transcription of ybt genes encoding biosynthetic and transport functions is repressed under excess iron conditions by Fur, but is also activated by Ybt via the transcr...

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Hlavní autoři: Miller, M. Clarke, Fetherston, Jacqueline D., Pickett, Carol L., Bobrov, Alexander G., Weaver, Robert H., DeMoll, Edward, Perry, Robert D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Microbiology Society 2010
Témata:
Microbial Pathogenicity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068685/
https://ncbi.nlm.nih.gov/pubmed/20413552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.037945-0
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