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Two regulatory elements required for enhancing ospA expression in Borrelia burgdorferi grown in vitro but repressing its expression during mammalian infection

During cycling between the tick vector and a mammal, the Lyme disease spirochaete Borrelia burgdorferi must coordinate expression of outer-surface proteins (Osps) A and B to quickly respond to environmental changes. The pathogen abundantly produces OspA/B in the tick, but represses their expression...

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Hlavní autoři: Xu, Qilong, McShan, Kristy, Liang, Fang Ting
Médium: Artigo
Jazyk:Inglês
Vydáno: Microbiology Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068683/
https://ncbi.nlm.nih.gov/pubmed/20395273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.036608-0
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