H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence

Animal research supports a central role for corticotropin releasing factor (CRF) in actions of ethanol on brain function. An examination of alcohol consumption in adolescents reported a significant genotype × environment (G × E) interaction involving rs1876831, a CRHR1 polymorphism, and negative eve...

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Hauptverfasser: Nelson, Elliot C., Agrawal, Arpana, Pergadia, Michele L., Wang, Jen C., Whitfield, John B., Saccone, F. Scott, Kern, Jason, Grant, Julia D., Schrage, Andrew J., Rice, John P., Montgomery, Grant W., Heath, Andrew C., Goate, Alison M., Martin, Nicholas G., Madden, Pamela A.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068622/
https://ncbi.nlm.nih.gov/pubmed/19878140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2009.00181.x
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