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Systems Pharmacology of Arrhythmias

Long-QT syndrome (LQTS) is a congenital or drug-induced change in electrical activity of the heart that can lead to fatal arrhythmias. Mutations in 12 genes encoding ion channels and associated proteins are linked with congenital LQTS. With a computational systems biology approach, we found that gen...

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Autori principali: Berger, Seth I., Ma’ayan, Avi, Iyengar, Ravi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068558/
https://ncbi.nlm.nih.gov/pubmed/20407125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000723
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