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Single strand targeted triplex-formation. Destabilization of guanine quadruplex structures by foldback triplex-forming oligonucleotides.

Oligonucleotides that can hybridize to single-stranded complementary polypurine nucleic acid targets by Watson-Crick base pairing as well as by Hoogsteen base pairing, referred to here as foldback triplex-forming oligonucleotides (FTFOs), have been designed. These oligonucleotides hybridize with tar...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Kandimalla, E R, Agrawal, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1995
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7537368/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.6.1068
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