Neuromyelitis optica unique area postrema lesions: Nausea, vomiting, and pathogenic implications

OBJECTIVE: To characterize the neuropathologic features of neuromyelitis optica (NMO) at the medullary floor of the fourth ventricle and area postrema. Aquaporin-4 (AQP4) autoimmunity targets this region, resulting in intractable nausea associated with vomiting or hiccups in NMO. METHODS: This neuro...

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Main Authors: Popescu, B.F.Gh., Lennon, V.A., Parisi, J.E., Howe, C.L., Weigand, S.D., Cabrera-Gómez, J.A., Newell, K., Mandler, R.N., Pittock, S.J., Weinshenker, B.G., Lucchinetti, C.F.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068006/
https://ncbi.nlm.nih.gov/pubmed/21368286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318214332c
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