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Initiation of RNA-primed DNA synthesis in vitro by DNA polymerase alpha-primase.
The initiation of new DNA strands at origins of replication in animal cells requires de novo synthesis of RNA primers by primase and subsequent elongation from RNA primers by DNA polymerase alpha. To study the specificity of primer site selection by the DNA polymerase alpha-primase complex (pol alph...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1995
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306798/ https://ncbi.nlm.nih.gov/pubmed/7537367 |
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