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The effect of TNFα on food intake and central insulin sensitivity in rats

Circulating and tissue levels of the proinflammatory cytokine tumor necrosis factor α (TNFα) are elevated in obesity. TNFα interferes with insulin signaling in many tissues and also plays a causal role in the anorexia that accompanies severe challenges to the immune system. The interactions between...

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Detalhes bibliográficos
Main Authors: de Kloet, Annette D., Pacheco-López, Gustavo, Langhans, Wolfgang, Brown, Lynda M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067978/
https://ncbi.nlm.nih.gov/pubmed/21163282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2010.11.037
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