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JNK1 Is Required for Lentivirus Entry and Gene Transfer

Although a lot of progress has been made in development of lentiviral vectors for gene therapy, the interactions of these vectors with cellular factors have not been explored adequately. Here we show that lentivirus infection phosphorylates JNK and that blocking the kinase activity of JNK decreases...

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Autores principales: Lee, Meng-Horng, Padmashali, Roshan, Andreadis, Stelios T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067971/
https://ncbi.nlm.nih.gov/pubmed/21191018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01765-10
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