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Initiation of Epstein-Barr Virus Lytic Replication Requires Transcription and the Formation of a Stable RNA-DNA Hybrid Molecule at OriLyt

The genetic elements of herpesvirus origins of lytic replication have been characterized in detail; however, much remains to be elucidated concerning their functional role in replication initiation. In the case of the Epstein-Barr virus (EBV), we have found that in addition to the two well-defined c...

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Detalhes bibliográficos
Main Authors: Rennekamp, Andrew J., Lieberman, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067963/
https://ncbi.nlm.nih.gov/pubmed/21191028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02175-10
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