Glutamic acid decarboxylase and glutamate receptor changes during tolerance and dependence to benzodiazepines
Protracted administration of diazepam elicits tolerance, whereas discontinuation of treatment results in signs of dependence. Tolerance to the anticonvulsant action of diazepam is present in an early phase (6, 24, and 36 h) but disappears in a late phase (72–96 h) of withdrawal. In contrast, signs o...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248104/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051628698 |
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