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Reversal of Heterochromatic Silencing of Quiescent Herpes Simplex Virus Type 1 by ICP0
Persisting latent herpes simplex virus genomes are to some degree found in a heterochromatic state, and this contributes to reduced gene expression resulting in quiescence. We used a relatively long-term quiescent infection model in human fibroblasts, followed by provision of ICP0 in trans, to deter...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067893/ https://ncbi.nlm.nih.gov/pubmed/21191021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02263-10 |
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