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A new approach to the synthesis of the 5'-deoxy-5'-methylphosphonate linked thymidine oligonucleotide analogues.

A new synthetic method for the preparation of the 5'-deoxy-5'-methylphosphonate linked thymidine oligonucleotides (5'-methylenephosphonate analogues) was developed. The method is based on the use of a phosphonate protecting group, 4-methoxy-1-oxido-2-picolyl, enabling intramolecular n...

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Bibliografiset tiedot
Päätekijät: Szabó, T, Kers, A, Stawinski, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC306782/
https://ncbi.nlm.nih.gov/pubmed/7731801
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