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Rhesus and Human Cytomegalovirus Glycoprotein L Are Required for Infection and Cell-to-Cell Spread of Virus but Cannot Complement Each Other

Rhesus cytomegalovirus (RhCMV), the homolog of human cytomegalovirus (HCMV), serves as a model for understanding the pathogenesis of HCMV and for developing candidate vaccines. In order to develop a replication-defective virus as a vaccine candidate, we constructed RhCMV with glycoprotein L (gL) del...

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Detalhes bibliográficos
Main Authors: Bowman, J. Jason, Lacayo, Juan C., Burbelo, Peter, Fischer, Elizabeth R., Cohen, Jeffrey I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067789/
https://ncbi.nlm.nih.gov/pubmed/21191007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01970-10
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