Cpa, the Outer Membrane Protease of Cronobacter sakazakii, Activates Plasminogen and Mediates Resistance to Serum Bactericidal Activity

Cronobacter spp. are emerging neonatal pathogens in humans, associated with outbreaks of meningitis and sepsis. To cause disease, they must survive in blood and invade the central nervous system by penetrating the blood-brain barrier. C. sakazakii BAA-894 possesses an ∼131-kb plasmid (pESA3) that en...

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Detalhes bibliográficos
Main Authors: Franco, A. A., Kothary, M. H., Gopinath, G., Jarvis, K. G., Grim, C. J., Hu, L., Datta, A. R., McCardell, B. A., Tall, B. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067567/
https://ncbi.nlm.nih.gov/pubmed/21245266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01165-10
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