Experimental Infection with Schistosoma mansoni in CCR5-Deficient Mice Is Associated with Increased Disease Severity, as CCR5 Plays a Role in Controlling Granulomatous Inflammation

The plasma level of the chemokine CCL3 is elevated in patients with chronic severe schistosomiasis mansoni. We have previously shown that CCL3(−/−) mice with experimental infection showed diminished pathology and worm burden compared to those of wild-type (WT) mice. To elucidate further the role of...

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Detalhes bibliográficos
Main Authors: Souza, Adriano L. S., Souza, Patrícia R. S., Pereira, Cíntia A., Fernandes, Adriana, Guabiraba, Rodrigo, Russo, Remo C., Vieira, Leda Q., Corrêa, Ary, Teixeira, Mauro M., Negrão-Corrêa, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067544/
https://ncbi.nlm.nih.gov/pubmed/21263020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00502-10
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