Evaluation of the Immunogenicity and Biological Activity of the Citrobacter freundii Vi-CRM(197) Conjugate as a Vaccine for Salmonella enterica Serovar Typhi

Typhoid fever remains a major health problem in developing countries. Young children are at high risk, and a vaccine effective for this age group is urgently needed. Purified capsular polysaccharide from Salmonella enterica serovar Typhi (Vi) is licensed as a vaccine, providing 50 to 70% protection...

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Bibliographic Details
Main Authors: Rondini, Simona, Micoli, Francesca, Lanzilao, Luisa, Hale, Christine, Saul, Allan J., Martin, Laura B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Vaccine Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067394/
https://ncbi.nlm.nih.gov/pubmed/21248155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00387-10
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