The Lower Serum Immunoglobulin G2 Level in Severe Cases than in Mild Cases of Pandemic H1N1 2009 Influenza Is Associated with Cytokine Dysregulation

The majority of patients with pandemic influenza H1N1 2009 had mild illness, but some, including those with no risk factors for severe disease, may succumb to this infection. Besides viral factors such as the D222/225G substitution of the hemagglutinin, host factors such as IgG2 subclass deficiency...

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Detalhes bibliográficos
Main Authors: Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Tse, Herman, Lau, Candy Choi-Yi, Li, Iris Wai-Sum, Hung, Ivan Fan-Ngai, Chan, Kwok-Hung, Cheng, Vincent Chi-Chung, Lai, Thomas Sik-To, Woo, Patrick Chiu-Yat, Chan, Eric Yuk-Tat, Yuen, Kwok-Yung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Microbial Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067346/
https://ncbi.nlm.nih.gov/pubmed/21123524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00363-10
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