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New Insights into the Genetic Organization of the FK228 Biosynthetic Gene Cluster in Chromobacterium violaceum No. 968
The biosynthetic gene cluster of FK228, an FDA-approved anticancer natural product, was identified and sequenced previously. The genetic organization of this gene cluster has now been delineated through systematic gene deletion and transcriptional analysis. As a result, the gene cluster is redefined...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067218/ https://ncbi.nlm.nih.gov/pubmed/21183645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01512-10 |
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