In Vitro and In Vivo Properties of BAL30376, a β-Lactam and Dual β-Lactamase Inhibitor Combination with Enhanced Activity against Gram-Negative Bacilli That Express Multiple β-Lactamases

BAL30376 is a triple combination comprising a siderophore monobactam, BAL19764; a novel bridged monobactam, BAL29880, which specifically inhibits class C β-lactamases; and clavulanic acid, which inhibits many class A and some class D β-lactamases. The MIC(90) was ≤4 μg/ml (expressed as the concentra...

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Detalhes bibliográficos
Main Authors: Page, Malcolm G. P., Dantier, Clothilde, Desarbre, Eric, Gaucher, Bérangère, Gebhardt, Klaus, Schmitt-Hoffmann, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067176/
https://ncbi.nlm.nih.gov/pubmed/21245441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01370-10
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