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Characterization of the Biosynthesis Gene Cluster for the Pyrrole Polyether Antibiotic Calcimycin (A23187) in Streptomyces chartreusis NRRL 3882

The pyrrole polyether antibiotic calcimycin (A23187) is a rare ionophore that is specific for divalent cations. It is widely used as a biochemical and pharmacological tool because of its multiple, unique biological effects. Here we report on the cloning, sequencing, and mutational analysis of the 64...

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Bibliografiske detaljer
Main Authors: Wu, Qiulin, Liang, Jingdan, Lin, Shuangjun, Zhou, Xiufen, Bai, Linquan, Deng, Zixin, Wang, Zhijun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067094/
https://ncbi.nlm.nih.gov/pubmed/21173184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01130-10
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