Posaconazole Serum Concentrations among Cardiothoracic Transplant Recipients: Factors Impacting Trough Levels and Correlation with Clinical Response to Therapy

Fifty-six serum posaconazole trough levels were measured in 17 cardiothoracic transplant recipients. Initial levels were ≤0.5, 0.51 to 0.99, and ≥1 μg/ml for 47, 29, and 24% of patients, respectively. Median trough levels associated with therapeutic success were higher than those associated with fai...

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Autors principals: Shields, Ryan K., Clancy, Cornelius J., Vadnerkar, Aniket, Kwak, Eun J., Silveira, Fernanda P., Massih, Rima C. Abdel, Pilewski, Joseph M., Crespo, Maria, Toyoda, Yoshiya, Bhama, Jay K., Bermudez, Christian, Nguyen, M. Hong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067082/
https://ncbi.nlm.nih.gov/pubmed/21189337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01325-10
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